In this issue of Blood , Nagy et al developed a novel Gp1ba-Cre mouse that uses the endogenous Gp1ba locus that encodes the glycoprotein Ibα (GPIbα) subunit of the GPib-IX receptor to drive Cre expression in murine megakaryocytes (MKs) for targeted ablation of floxed genes. 1
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Gollomp et al. (2019) studied this question.
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