What does this research mean for the field?

Neither metoprolol nor labetalol serves as an optimal low/high-permeability class boundary standard for the Biopharmaceutics Classification System, as metoprolol is overly conservative and labetalol is subject to P-gp-mediated efflux transport. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

April 3, 2014Molecular Pharmaceutics

The Low/High BCS Permeability Class Boundary: Physicochemical Comparison of Metoprolol and Labetalol

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Authors

MZMoran Zur MGMarisa Gasparini OWOmri Wolk

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Cite This Study

Zur et al. (2014) studied this question.

synapsesocial.com/papers/6aa95d63f8a0f2477726484c https://doi.org/10.1021/mp500152y

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April 3, 2014Molecular Pharmaceutics

The Low/High BCS Permeability Class Boundary: Physicochemical Comparison of Metoprolol and Labetalol

View Full Paper

Ask AI

Bookmark

Authors

MZMoran Zur MGMarisa Gasparini OWOmri Wolk

Discussion

Member takes

Overview

Key Points

Key points are not available for this paper at this time.

Cite This Study

Zur et al. (2014) studied this question.

synapsesocial.com/papers/6aa95d63f8a0f2477726484c https://doi.org/10.1021/mp500152y

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