The use of a mediator to detect a nonabsorbing analyte during spectroelectrochemical modulation is demonstrated. The charge-selective composite film of Nafion-SiO2 was used to entrap the mediator, Ru(bipy)3(2+). The change in deltaA as detected by attenuated total reflection was then observed upon addition of the analyte, ascorbate. The effects of scan rate, concentration of mediator, film thickness, and analyte charge were studied to achieve optimal sensor conditions. The model sensor exhibited a linear range from 0.26 to 2.0 mM (R2 = 0.998).
No takes yet. Share an insight, caveat, or question.
DiVirgilio-Thomas et al. (2000) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: