Answers are grounded in this paper and cite their sources.
Intravenous somatostatin boluses produced striking diminution in portal vein blood flow in dogs (maximally 40--55%). This effect was of rapid onset, without observable changes in hepatic artery flow, systemic blood pressure, pulse or central venous pressure. The duration of action was short, but could be sustained by continuous intravenous infusion. These observations are consistent with an endocrine role of somatostatin in the regulation of nutrient balance.
No takes yet. Share an insight, caveat, or question.
Jaspan et al. (1979) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: