Comparison of clinical outcomes between Wavelight Allegretto Eye-Q and Schwind Amaris 1050RS in high myopic astigmatism

Purposes: To compare clinical outcomes between Wavelight Allegretto Eye-Q 400Hz and Schwind Amaris 1050RS in high myopic astigmatism. Methods: non-randomized, controlled, interventional study of 90 eyes with at least 1.5diopter astigmatism, assigned into two groups depends to the L machine and followed up three months post-op. Primary outcomes include uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), subjective refraction spherical equivalent (SRSE), cylinder, safety and efficacy indices, refractive predictability and stability; and optical aberration and contrast sensitivity changes after surgery. Besides, Alpins method about residual astigmatism is also analyzed and compared between groups. Results: Safety index of Schwind Amaris and Allegretto group is 1.011 ± 0.169 and 1.007 ± 0.055 (p = 0.510); effective index is 1 ± 0.032 and 0.991 ± 0.077 (p = 0.567; stability index is 0.003 and 0.1 (p = 0.134); predictability index within [±0.5D] after three-month postop is 91.1% and 95.6% (p = 0.398), respectively. Post-op residual astigmatism in Schwind Amaris and Allegretto group is -0.139 ± 0.22 and -0.183 ± 0.27 (p = 0.396). Regarding Alpins method in astigmatic analysis of Schwind Amaris and Allegretto groups: SIA (surgically induced astigmatism) is 1.792 ± 0.534 and 1.920 ± 0.588 (p = 0.284); AE (angle of error) is 1.04 ± 2.881 and -0.08 ± 3.790 (p = 0.119); CI (correction index) is 0.98 ± 0.107 and 1.02 ± 0.142 (p = 0.165); SAS (Success of Astigmatism Surgery) is 92.01 ± 12.77 and 89.78 ± 16.32 (p = 0.472), respectively. Contrast sensitivity and higher optical aberration changes after surgery between two groups are insignificant differences (p > 0.05). Conclusions: Clinical outcomes of both lasers machine are good. There is no significant differences in residual astigmatism and high-order aberrations or contrast sensitivity changes after surgery between two groups.