The stereoselective syntheses of diastereomers of antitumor natural pericosine A from (-)-quinic acid were achieved. One of the diastereomers, methyl (3R,4S,5S,6R)-6-chloro-3,4,5-trihydroxycyclohex-1-enecarboxylate, possesses the reported structure of pericosine A. The reported relative configuration of natural pericosine A was shown to be incorrect.
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Usami et al. (2007) studied this question.
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