July 1, 2002Journal of Clinical Investigation
Influenza vaccines: present and future
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Key result
Influenza epidemics drive significant morbidity and cause ~20,000 US deaths annually.
Why the study?
The impact of influenza on individuals and society remains underappreciated despite significant morbidity and mortality.
Population
Up to 20% of the population affected by influenza annually in the US
Design
Review
Authors
Discussion
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Implication
Improved influenza vaccines may reduce US deaths and hospitalizations; leaves open optimal design strategies pending rigorous trials.
PICO
P
Population
Influenza
E
Exposure / Comparator
Influenza vaccines
Highlights the significant historical and ongoing public health burden of influenza, emphasizing the need for continued vaccine development.
Cite This Study
Palese et al. (2002) conducted a review in Influenza. Influenza vaccines was evaluated. Influenza epidemics cause significant morbidity and mortality, affecting up to 20% of the population annually and causing an average of 20,000 deaths per year in the US.
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