Key result
Polygenic trait mapping in animal models promises to revolutionize the understanding of atherosclerosis risk.
Why the study?
New methods for mapping and analysis of polygenic traits in animal models are being applied to study risk factors for atherosclerosis, promising advances in understanding the disease.
The application of new methods for mapping polygenic traits in animal models promises to advance the understanding of atherosclerosis and its associated risk factors.
Answers are grounded in this paper and cite their sources.
Does not support clinical practice changes; leaves open whether animal polygenic mapping will advance human atherosclerosis risk assessment.
With the recent development of methods for the mapping and analysis of polygenic traits in animal models, a new era in animal genetics has begun. These methods are now being applied to the analysis of various risk factors for atherosclerosis, including hyperlipidemia, hypertension, obesity and diabetes. Such studies promise to revolutionize the understanding of atherosclerosis and other complex human disease
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Lusis et al. (1992) conducted a review in Atherosclerosis. Recent developments in mapping and analyzing polygenic traits in animal models are being applied to atherosclerosis risk factors, promising to revolutionize the understanding of complex human diseases.
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