External constraints are necessary in order to calculate the energetics of embryo formation when the embryo is not a critical nucleus. The expression for the reversible work of formation obtained in by Debenedetti and Reiss [J. Chem. Phys. 108, 5498 (1998)] is rigorous and valid regardless of the relative densities of the embryo and mother phase.
No takes yet. Share an insight, caveat, or question.
Debenedetti et al. (1999) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: