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January 1, 2015RSC Advances

Design of dual MMP-2/HDAC-8 inhibitors by pharmacophore mapping, molecular docking, synthesis and biological activity

Amit Kumar Halder Sumana Mallick Deep Shikha Achintya Saha Krishna Das Saha Tarun Jha

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Abstract

Recent analyses have highlighted the promotion of cancer migration and invasion, mediated through HDAC via MMP-2 and MMP-9.

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Halder et al. (2015) studied this question.

synapsesocial.com/papers/6aa9f2742f1eb85158fc95a7 https://doi.org/10.1039/c5ra12606a

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