Unavailability of apposite diagnostic test capable of monitoring early stage progression/relapse of lung cancer is related to its high mortality rate wordwide.We report for the first time detection of lung cancer biomarker hTERT (human telomerase reverse transcriptase), using anti-hTERT for fabrication of graphene oxide (a low cost unique multifunctional material) based immunosensor in spiked sputum samples in the dynamic detection range of 100 fg mL -1 -10 ng mL -1 in 30 s exposure time.The easy fabrication of above said electrochemical immunosensor warrants the development of low cost and non invasive diagnostics (first and second stages) for lung cancer.
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Meenakshi Choudhary (2013) studied this question.
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