Key result
Gastric cancer pulmonary tumor thrombotic microangiopathy mimics chemical inhalation injury with 1-month survival post-chemotherapy.
Case Report (n=1)
PTTM can present similarly to chemical inhalation lung injury, making biopsy crucial for accurate diagnosis.
Alerts clinicians to PTTM mimicking inhalation injury; extends sparse case data on chemotherapy survival in occult gastric cancer.
Pulmonary tumor thrombotic microangiopathy (PTTM) is a complication characterized by dyspnea, pulmonary hypertension, and occasionally sudden death. We encountered a man who developed PTTM and had an inhalation history of chemical herbicides and abnormal findings on chest computed tomography, mimicking chemical inhalation lung injury. He was diagnosed with PTTM with adenocarcinoma by a transbronchial lung biopsy and received chemotherapy and anticoagulant therapy. He survived for one month. An autopsy revealed primary gastric cancer with PTTM that can have a presentation similar to diffuse pulmonary diseases, including chemical inhalation lung injury. The examination of a biopsy specimen is crucial in such patients.
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Tateishi et al. (2019) conducted a case report in Pulmonary tumor thrombotic microangiopathy (PTTM) (n=1). Chemotherapy and anticoagulant therapy was evaluated on Clinical outcome. A 75-year-old man with pulmonary tumor thrombotic microangiopathy secondary to occult gastric cancer presented with symptoms mimicking chemical inhalation lung injury and survived for one month after chemotherapy.
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