Key result
Alvimopan is associated with advancing diet >24 hours earlier versus no alvimopan after radical cystectomy.
Why the study?
Postoperative ileus is a common complication after urinary diversion using bowel segments, and there are no documented studies on alvimopan's efficacy in urologic surgery.
Does alvimopan reduce time to dietary advancement and length of hospital stay in patients undergoing radical cystectomy with ileal diversion?
Cohort (n=16)
Does alvimopan reduce time to dietary advancement and length of hospital stay in patients undergoing radical cystectomy with ileal diversion?
Alvimopan may reduce time to dietary advancement in patients undergoing radical cystectomy with ileal diversion.
May reduce POI after cystectomy; leaves open efficacy in urologic patients pending RCTs.
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Katz et al. (2013) conducted a cohort in Postoperative ileus (n=16). Alvimopan vs. Alvimopan naive group was evaluated on Time to dietary advancement. Alvimopan use in patients undergoing radical cystectomy with ileal diversion was associated with advancing diet more than 24 hours earlier compared to the alvimopan naive group.
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