Immunomodulation Therapy – Clinical Relevance of Bacterial Lysates OM-85

Respiratory tract infections (RTIs) affect children and adults with chronic respiratory conditions throughout the world. As RTIs can often recur, they confer a significant morbidity and mortality burden and represent an important unmet medical need. Studies have shown that the bacterial lysates OM-85 can activate both innate and adaptive immune responses via maturation of gut mucosal dendritic cells, resulting in the homing of immune cells to lymphoid tissue in the lungs and subsequent antibody production.