Diversification to meet demand: The growing demand for novel radiopharmaceuticals can only be met through the development of new approaches to isotopic labeling. Effective strategies for 11C labeling are highlighted with emphasis on reactions with [11C]carbon dioxide and [11C]methyl iodide (see scheme). DBU=1,8-diazabicyclo[5.4.0]undec-7-ene, TMAO=trimethylamine N-oxide.
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Peter J. H. Scott (2009) studied this question.
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