Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 9, 2020Molecular Biology of the CellOpen Access

Cholesterol-lowering drugs reduce APP processing to Aβ by inducing APP dimerization

View Full Paper
Ask AI
Bookmark
Share

Authors

VLVanessa F. LangnessRKRik van der KantUDUtpal Das

Discussion

Loading...

Member takes

Overview

Key Points

Key points are not available for this paper at this time.

Cite This Study

Langness et al. (2020) studied this question.

synapsesocial.com/papers/6aaa1334207060c46bfbc0efhttps://doi.org/10.1091/mbc.e20-05-0345
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Visualization of APP dimerization and APP‐Notch2 heterodimerization in living cells using bimolecular fluorescence complementation2006 · 66 citations
  2. 2The GxxxG motif: A framework for transmembrane helix-helix association2000 · 949 citations
  3. 3Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 102001 · 802 citations
  4. 4Local cholesterol increase triggers amyloid precursor protein‐Bacel clustering in lipid rafts and rapid endocytosis2011 · 183 citations