Key result
Prospective designs and strict protocol adherence ensure valid results in sample-based research.
Why the study?
The importance of prospective research design and adherence to pre-specified plans in sample-based research was highlighted by recent heart failure studies.
Design
Review article explaining research design principles
Authors
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Upholds methodological standards for validity; leaves open optimal enforcement strategies in cardiovascular trials.
Key points are not available for this paper at this time.
Lemuel A. Moyé (2001) reported a review. Prospective research design and adherence to predefined protocols are essential in sample-based research to ensure valid and reliable results.
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