Current bioinks for cell-based 3D bioprinting are not suitable for technology scale-up due to the challenges of cell sedimentation, cell membrane damage, and cell dehydration. A new self-assembling bio-ink is designed to enable 3D bio-printing of multiple cell types into an aqueous bath on page 2488 by Sarah C. Heilshorn and co-workers, to overcome these three major hurdles. Artwork designed by Karen Dubbin and Nick Suhar.
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Dubbin et al. (2016) studied this question.