An Update Review on the Paneth Cell as Key to Ileal Crohn's Disease

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum2010 · 166 citations
2. 2LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn’s disease patients2017 · 68 citations
3. 3Butyric Acid and Leucine Induce α-Defensin Secretion from Small Intestinal Paneth Cells2019 · 90 citations
4. 4Host Defense Peptide Resistance Contributes to Colonization and Maximal Intestinal Pathology by Crohn's Disease-Associated Adherent-Invasive Escherichia coli2014 · 72 citations
5. 5Alpha-defensins (α-Defs) in Crohn's disease: decrease of ileal α-Def 5 via permanent methylation and increase in plasma α-Def 1-3 concentrations offering biomarker utility2017 · 11 citations