A Simple, Recyclable, Polymer-Supported Palladium Catalyst for Suzuki Coupling—an Effective Way to Minimize Palladium Contamination

To address the challenges encountered in homogeneous catalytic processes, such as the minimization of metal contamination and the recycling of the catalysts, a polymer-supported palladium catalyst for Suzuki coupling was developed. The application of this heterogeneous palladium catalyst to the synthesis of a novel, amino-tetralin type, pharmaceutical ingredient led to a very low residual palladium content (<1.1 ppm).