Amination of Aliphatic Alcohols and Diols with an Iridium Pincer Catalyst

Best aminated feature: Catalytic transformation of alcohols to amines is a fundamental transformation in synthetic organic chemistry. A general salt-free Ir-catalyzed amination of aliphatic alcohols and diols has been developed, which gives amino alcohols with high selectivity. By use of an Ir–pincer chlorodihydride complex, usually applied for the transfer hydrogenation of ketones, simple monoalcohols are aminated with excellent yields.