Bioinformatics resource report presents a curated viral protein database with hidden Markov models, facilitating sensitive detection of divergent viral sequences.
We present RVDB-prot, a database corresponding to the protein equivalent of the nucleic acid reference virus database RVDB. Protein databases can be helpful to perform more sensitive protein sequence comparisons. Similarly to its homologous public repository, RVDB-prot aims to provide reliable and accurately annotated unique entries, while including also an Hidden Markov Model (HMM) protein profiles database for distant protein searching.
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Bigot et al. (2019) studied this question.
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