interference with the potassium method on the DT60 analyzer but a 38% decrease was seen with lipaemic serum.The exact reason for the difference be- tween interference by Intralipid and lipaemic sewn samples is unknown; differences in light scattering properties of the lipids in the two different matrices could account for the observed differences.Thus the standard way of assessing lipaemic interference (that is, the addition of Intralipid to serum) may not be appropriate for assessing lipaemic interference in all cases.We are not aware of any previous studies addressing this important issue; it is clear that further studies evaluating the different effects of lipaemic serum samples and Intralipid on other analysers are necessary.
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Cohen et al. (1988) studied this question.
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