Key result
Ashkenazy male fetuses and children show more developed coronary intima and musculo-elastic layers than other groups.
Why the study?
Differences in coronary artery structural development among ethnic groups and sexes in early life and their relation to adult coronary heart disease prevalence were unclear.
Population
211 consecutive necropsy specimens of full-term fetuses, infants, and children from Ashkenazy, Yemenite, and Bedouin groups
Comparison
Coronary artery histologic features among Ashkenazy, Yemenite, and Bedouin ethnic groups and between sexes
Design
Observational histologic study of necropsy specimens
Authors
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Early ethnic-sex differences in coronary histology may inform adult CHD epidemiology; hypothesis-generating with no clinical implications.
Observational (n=211)
Structural differences in the coronary arteries are present in early life among different ethnic groups and sexes, which may correlate with the reported prevalence of coronary heart disease in the corresponding adult populations.
Vlodaver et al. (1969) reported an observational. Ethnicity and sex vs. Other ethnic groups and opposite sex was evaluated on Histologic changes in the coronary arteries. Histologic examination of coronary arteries in 211 fetuses and children under 10 years showed the intima and musculo-elastic layers were more developed in Ashkenazy males than in other groups.