The clinical outcome of coronavirus disease 2019 (COVID-19) varies considerably from one individual to another and severe illness occurs only in a minority of cases.Evidence supports the role of genetic background alongside host, viral and environmental factors for COVID-19 severity.It seems that host genetic background affects the balance of immune responses during SARS-CoV-2 infection, leading to different clinical courses of the disease.
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Alireza Tahamtan (2020) studied this question.
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