Key result
Infraslow neurofeedback reduces food craving and increases posterior cingulate activity vs placebo in obese women.
Why the study?
The posterior cingulate cortex is involved in food craving in obese food addicted individuals, but the therapeutic effects of infraslow neurofeedback targeting this region were unexplored.
Does infraslow neurofeedback reduce food craving and alter electrophysiological activity in obese women with food addiction?
RCT (n=24)
Double-blind
Block randomization
No
Does infraslow neurofeedback reduce food craving and alter electrophysiological activity in obese women with food addiction?
Infraslow neurofeedback targeting the posterior cingulate cortex may alter electrophysiological activity and reduce food craving in obese women with food addiction.
The posterior cingulate cortex (PCC) is involved in food craving in obese food addicted individuals. This randomised, double-blind, placebo-controlled parallel study explored the potential therapeutic effects of infraslow neurofeedback (ISF-NF) on food craving targeting the PCC in obese women with symptoms of food addiction. Participants received six sessions of either ISF-NF (n = 11) or placebo (n = 10) over a three-week period. There were no reported adverse effects. Electrophysiologically, there were significant increases in infraslow activity (p = 0.0002) and infraslow/beta nesting (p < 0.001) in the PCC in the ISF-NF group (mean r = 0.004 ± 0.002) compared to placebo (mean r = 0.02 ± 0.002) two days after the last intervention. Also, there was a significant decrease in different dimensions of state food craving compared to baseline and to placebo. Findings suggest that source localized IFS-NF results in electrophysiological changes and may be associated with reduced food craving. This trial is registered at www.anzctr.org.au , identifier, ACTRN12617000601336. This study was funded by the Otago Medical Research Grant: CT375.
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Leong et al. (2018) conducted an RCT in Food addiction and obesity (n=24). Infraslow neurofeedback (ISF-NF) vs. Placebo (simulation ISF-NF) was evaluated on Resting state EEG and source localisation (infraslow band activity in the posterior cingulate cortex) (p=0.034). Infraslow neurofeedback significantly increased infraslow activity and infraslow/beta nesting in the posterior cingulate cortex and reduced state food craving compared to placebo in obese women.
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