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UNLABELLED: : Hilbert curves enable high-resolution visualization of genomic data on a chromosome- or genome-wide scale. Here we present the HilbertCurve package that provides an easy-to-use interface for mapping genomic data to Hilbert curves. The package transforms the curve as a virtual axis, thereby hiding the details of the curve construction from the user. HilbertCurve supports multiple-layer overlay that makes it a powerful tool to correlate the spatial distribution of multiple feature types. AVAILABILITY AND IMPLEMENTATION: The HilbertCurve package and documentation are freely available from the Bioconductor project: http://www.bioconductor.org/packages/devel/bioc/html/HilbertCurve.html CONTACT: m.schlesner@dkfz.de SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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Gu et al. (2016) studied this question.
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