Clinical review highlights low-energy diets as viable weight-loss interventions in early-stage chronic kidney disease, suggesting novel dietary pathways to slow disease progression.
Nearly half of adults with CKD are obese, and obesity is a modifiable risk factor for CKD progression.1 Numerous obesity treatments exist for patients with CKD, including bariatric surgery and prescription medications. While these treatments are successful, dietary modification remains a central component of all obesity treatments in CKD.2 One form of dietary modification shown to be effective in non-CKD patients is low-energy diets (LED). LED, defined as eating 800-1000 kcal/day, involve replacing most or all usual dietary intake with meal replacements (e.g., shakes, bars, soups) to induce a caloric deficit.
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Lorenz et al. (2025) studied this question.
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