Muscle and Liver Insulin Resistance Indexes Derived From the Oral Glucose Tolerance Test

It was recently reported (1) that it is important to assess both hepatic and muscle insulin resistance because doing so can lead to different treatment approaches according to the insulin resistance status of each organ. Currently, the hyperinsulinemic-euglycemic clamp is the gold standard for the measurement of liver and muscle insulin sensitivity (2). However, this method is unpractical in clinical practice. For this reason, Abdul-Ghani et al. (1) developed several formulas that were derived from an oral glucose tolerance test (OGTT) for the assessment of …