Why the study?
Synovial sarcoma of the head and neck is uncommon and rarely found in the oral cavity, especially on the floor of the mouth.
Case Report (n=1)
Immunohistological analysis is crucial for confirming the diagnosis of rare synovial sarcoma in the oral cavity to prevent misdiagnosis and delayed treatment.
BACKGROUND: Head and neck Synovial sarcoma (SS) accounts for 3-10% of all total body SS. It is rare to find it in the oral cavity, especially on the floor of the mouth. CASE PRESENTATION: We present a 44-year-old Chinese male, who had been misdiagnosed as fibroadenoma, with a swelling on the right submandibular region for more than 3 months. The radiology examinations and the pathology results indicate the diagnosis of SS of the floor of the mouth. The patient only had a surgical operation, without radiotherapy and chemotherapy. At the first follow-up, the patient exhibited no clinical or radiographic complications, and the patient was asymptomatic on subsequent visits. CONCLUSIONS: Misdiagnosis results the delay of diagnosis and treatment of SS. Immunohistological analysis might be the most important tool to confirm the diagnosis of SS.
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Wang et al. (2020) conducted a case report in Synovial sarcoma of the floor of the mouth (n=1). Surgical resection was evaluated on Recurrence and metastasis.
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