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Tunable diode lasers (TDLs) are applied to the diagnostics of gastroenterological diseases using respiratory tests and preparations enriched with the stable 13 C isotope. This method of the analysis of the 13 C/ 12 C isotope ratio in CO 2 in exhaled air is based on the selective measurement of the resonance absorption at the vibrational — rotational structure of 12 CO 2 and 13 CO 2 . The CO 2 transmission spectra in the region of 4.35 μm were measured with a PbEuSe double-heterostructure TDL. The accuracy of carbon isotope ratio measurements in CO 2 of exhaled air performed with the TDL was ~0.5%. The data of clinical tests of the developed laser-based analyser are presented.
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Eugene V. Stepanov (2002) studied this question.
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