A practical I 2 -mediated aromatic C–H amination reaction was established for benzimidazol-2-one synthesis under transition-metal-free conditions. The present reaction can be performed directly from disubstituted amines and isocyanates without the purification of the urea intermediates in a scalable fashion.
No takes yet. Share an insight, caveat, or question.
Meng et al. (2018) studied this question.