Treatment of infantile spasms with high-dose oral prednisolone'Sir-Infantilespasms were first described by Dr WJ West in a letter to the Lancet in 1841.Most affected children have a poor neurological outcome, with continuing seizures and severe learning disability.Mthoughgenerally refractory to anti-epileptic drugs, treatment with steroid therapy has been shown to control seizures in matiypatients.Despite
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Amiel‐Tison et al. (1998) studied this question.
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