Key result
Low-profile disc prosthesis linked to ~80% lower in-hospital mortality vs caged ball in narrow LVO.
Why the study?
The impact of left ventricular outflow tract width on prosthesis selection and outcomes in mitral valve replacement was unclear.
Does the use of a low profile prosthesis compared to a caged ball prosthesis reduce mortality in mitral stenosis patients with a narrow left ventricular outflow tract (<20 mm) assessed by echocardiography?
Observational (n=26)
Does the use of a low profile prosthesis compared to a caged ball prosthesis reduce mortality in mitral stenosis patients with a narrow left ventricular outflow tract (<20 mm) assessed by echocardiography?
Absolute Event Rate: 71.4% vs 14.3%
Echocardiographic measurement of left ventricular outflow width is critical before mitral valve replacement, as a narrow LVO (<20 mm) requires a low-profile prosthesis to prevent fatal outflow obstruction.
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Narrow LVOT may favor low-profile prostheses in mitral replacement; this observational association leaves open randomized confirmation.
Nanda et al. (1973) conducted an observational in Mitral stenosis (n=26). Starr-Edwards (caged ball) prosthesis in narrow LVO (<20 mm) vs. Cross-Jones (disc) prosthesis in narrow LVO (<20 mm) was evaluated on In-hospital death. In patients with narrow left ventricular outflow (<20 mm), use of a caged ball prosthesis resulted in high in-hospital mortality (71.4%) compared to a low profile disc prosthesis (14.3%).