The polypeptide folds of two primary biological catalysts have been determined by X-ray crystallography. One is glutamine synthetase (GS) from Salmonella typhimurium, which catalyzes the entry of nitrogen into metabolism, and the other is ribulose bisphosphate carboxylase/oxygenase (RuBisCO) from tobacco, which catalyzes the entry of carbon into metabolism. Both are oligomeric structures having complicated patterns of interdomain and intersubunit contacts.
No takes yet. Share an insight, caveat, or question.
Eisenberg et al. (1987) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: