Key result
Heavy meromyosin S2 subunit shortening drives muscular contraction through thick and thin filament integration.
Describes the fundamental mechanism of muscle contraction via S(2) subunits of heavy meromyosin.
Muscular contraction is essentially the shortening of the S(2) subunits of heavy meromyosin, integrated to macroscopic motion by the thick and thin filaments.
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Albert Szent‐Györgyi (1974) studied this question. Muscular contraction occurs through the shortening of the S(2) subunits of heavy meromyosin, integrated into macroscopic motion by the thick and thin filaments.
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