Why the study?
The factors influencing operative mortality and long-term survival after coronary bypass surgery in patients with severe left ventricular dysfunction were assessed.
Cohort (n=102)
In patients with severe left ventricular dysfunction undergoing coronary bypass surgery, obesity, advanced age, and the need for preoperative intra-aortic balloon counterpulsation are independent risk factors for mortality.
Answers are grounded in this paper and cite their sources.
Supports preoperative risk assessment in severe LV dysfunction CABG; leaves open whether targeted strategies reduce mortality.
The results of coronary bypass surgery have been assessed in 102 patients with severe left ventricular dysfunction who had a preoperative left ventricular ejection fraction of ≤0.35 (mean(s.e.m.) 0.29 (0.01)). Independent risk factors influencing operative mortality were obesity ( P = 0.0290) and the need for preoperative intra-aortic balloon counterpulsation ( P = 0.0010). Cox regression analysis using as its end-point ‘cardiac-related death’ demonstrated three variables; the need for preoperative intra-aortic balloon counterpulsation ( P < 0.001), advanced age ( P = 0.011), and obesity ( P = 0.036). In a subset of 43 patients who did not have these risk factors, the 4-year cardiac-related death rate was 95.1 (3.4)%. The operative mortality and long-term survival can be expected to be satisfactory in patients with severe left ventricular dysfunction, provided they have a viable myocardium rather than myocardial fibrosis.
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Louagie et al. (1996) conducted a cohort in Severe left ventricular dysfunction (n=102). Coronary bypass surgery was evaluated on Cardiac-related death.
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