The Effect of an Exclusive Meat Diet Lasting One Year on the Carbohydrate Tolerance of Two Normal Men

During the past year exhaustive studies were made of the metabolism of two normal men whose diet consisted for 1 year exclusively of lean and fat meat.This was essentially a high fat, low carbohydrate diet.The tolerance of these men to carbohydrate was tested by the glucose meal.As far as can be ascertained, no experiments have been reported where subjects lived on a similar diet for 1 year.This communication presents such experiment,s.EXPEHI~MENTAL.The subjects were healthy adult men whose diet consisted soIely of lean and fat meat.This was eaten either cooked or raw.The protein of the diet averaged 120 gm. with a caloric intake of 2600 to 3000 calories.Other data and general plan of the experiment will be published by McClellan and Du Bois (1).Two glucose tolerance tests were carried out on each of the two sub- jects, K. A. and V. S.; one test immediately after the meat-fat diet was discontinued, the other 2 or more weeks after the general diet had been resumed.Some 8 or 9 hours after the first glucose tolerance test one of the men (K.A.) developed a pneumonia from which he recovered and reported in good condition for his second test 4 weeks later.Subject V. S.