Risk factors associated with canine heartworm infection were determined by screening medical records from the Veterinary Medical Data Program of June 1964--May 1976. Data represented were from 14 colleges and schools of veterinary medicine in the United States and Canada. A total of 3,655 dogs were infected. Intact male dogs 4 to 7 years old and of the larger hound breeds had the highest relative risk, whereas dogs of smaller breeds, those less than 2 years old, spayed females, and castrated males were at least risk.
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Selby et al. (1980) studied this question.
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