New chiral pyrazoles, (4R,7R)‐4‐methyl‐7‐isopropyl‐3‐phenyl‐ (3‐phenyliso menthopyrazole cis‐1), (4R,7S)‐4‐methyl‐7‐isopropyl‐ (1‐menthopyrazole; trans‐2), (4R,7R)‐4‐isopropyl‐7‐methyl‐ (iso carvomen‐thopyrazole, cis‐3) and (4R,7S)‐4‐isopropyl‐7‐methyl‐4,5,6,7‐tetrahydro‐1H‐indazole (carvomenthopyra‐zole, trans‐3) were prepared. The diastereomeric pairs of these 1–3 were structurally characterized by NMR spectroscopy. The subtle differences of structures of 1–3 should induce the useful effects for a chiral auxiliary or a chiral catalyst.
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Kashima et al. (2002) studied this question.
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