Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 17, 2019Journal of Chromatography BOpen Access

Simultaneous analysis of the total plasma concentration of atorvastatin and its five metabolites and the unbound plasma concentration of atorvastatin: Application in a clinical pharmacokinetic study of single oral dose

View Full Paper
Ask AI
Bookmark
Share

Authors

RCRoberta Natália CestariARAdriana RochaMMMaria Paula Marques

Discussion

Loading...

Member takes

Overview

Key Points

Key points are not available for this paper at this time.

Cite This Study

Cestari et al. (2019) studied this question.

synapsesocial.com/papers/6aab8054f062ce4e3ddfbb64https://doi.org/10.1016/j.jchromb.2019.121766
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1DFT study on hydroxy acid–lactone interconversion of statins: the case of fluvastatin2006 · 36 citations
  2. 2Exposure of atorvastatin is unchanged but lactone and acid metabolites are increased several-fold in patients with atorvastatin-induced myopathy2006 · 137 citations
  3. 3Simultaneous determination of atorvastatin and its metabolites in human plasma by UPLC-MS/MS2017 · 15 citations
  4. 4Development, validation and application of a novel HPLC-MS/MS method for the quantification of atorvastatin, bisoprolol and clopidogrel in a large cardiovascular patient cohort2018 · 22 citations