Key result
Vegetarian diet linked to lower plasma MPO and MMP levels versus an omnivorous diet.
Why the study?
Few studies have demonstrated the circulating profile of cardiovascular biomarkers in healthy vegetarians compared to omnivorous individuals.
Does a vegetarian diet improve the profile of circulating cardiovascular biomarkers in healthy men compared to an omnivorous diet?
Observational (n=84)
Does a vegetarian diet improve the profile of circulating cardiovascular biomarkers in healthy men compared to an omnivorous diet?
A vegetarian diet is associated with lower levels of circulating cardiovascular biomarkers such as MPO and MMPs in healthy men, suggesting a potentially protective cardiovascular profile.
Answers are grounded in this paper and cite their sources.
Should not yet change dietary advice; leaves open whether lower biomarkers reduce cardiovascular events.
BACKGROUND: Several evidences report that a vegetarian diet is protector against cardiovascular diseases. Few studies have demonstrated the circulating profile of cardiovascular biomarkers in vegetarians. Therefore, the aims of the current study were compared the plasma concentrations of myeloperoxidase (MPO), metalloproteinase (MMP)-9, MMP-2, tissue inhibitor of MMP (TIMP)-1 and TIMP-2 between healthy vegetarian (Veg) and healthy omnivorous (Omn). METHODS: Using ELISA and multiplexed bead immunoassay, we measured in plasma from 43 Veg and 41 Omn the cardiovascular biomarkers concentrations cited above. RESULTS: We found significant lower concentrations of MPO, MMP-9, MMP-2 and MMP-9/TIMP-1 ratio in Veg compared to Omn (all P<0.05). Moreover, MMP-9 concentrations were correlated positively with leukocytes and neutrophils count in both groups (all P<0.05). CONCLUSION: A vegetarian diet is associated with a healthier profile of cardiovascular biomarkers compared to omnivorous.
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Acosta‐Navarro et al. (2016) conducted an observational in Healthy (n=84). Vegetarian diet vs. Omnivorous diet was evaluated on Plasma concentrations of MPO, MMP-9, MMP-2, TIMP-1 and TIMP-2 (p=<0.05). A vegetarian diet in healthy men was associated with significantly lower plasma concentrations of MPO, MMP-9, MMP-2, and MMP-9/TIMP-1 ratio compared to an omnivorous diet (all P<0.05).
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