In Brief We have demonstrated in several studies that obesity and adipokines are more strongly associated with asthma in women than in men. The reason for this controversial sex difference is not known. Based on our previous studies, we hypothesize that sex-related differences in ectopic fat may explain the obesity-asthma association in women. Sex modification of the association of obesity and adipokines with asthma is controversial. This article discusses why sex differences might exist.
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A 2010 study studied this question.
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