Key result
2D-echo detects abnormalities in only 35% of patients with a pathologic pericardium despite high specificity.
Why the study?
Specific 2D-echocardiographic signs of pericardial disease require prospective validation including direct pathologic correlation.
Does 2D-echocardiography accurately detect pericardial abnormalities compared to pathology in pericardiectomy or autopsy patients?
Population
85 pericardiectomy or autopsy patients with 2D-echocardiography within 6 months
Comparison
2D-echocardiography vs pathology
Design
Blinded pericardial echocardiography-pathology correlation observational study
Follow-up
Within 6 months
Authors
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Echocardiography may confirm pericardial abnormalities when positive; leaves open its exclusion value and generalizability beyond pathology cohorts.
Observational (n=85)
Blinded
Does 2D-echocardiography accurately detect pericardial abnormalities compared to pathology in pericardiectomy or autopsy patients?
2D-echocardiography has low sensitivity (35%) but high specificity (90%) for detecting pericardial abnormalities when correlated with pathology.
Hinds et al. (1992) conducted an observational in Pericardial abnormalities (n=85). 2D-echocardiography vs. Pathology (autopsy or surgery) was evaluated on Detection of pericardial abnormalities. 2D-echocardiography detected pericardial abnormalities in 35% of patients with a pathologic pericardium, with an overall specificity of 90%.
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