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The observation of bacteria in a peripheral blood smear was conducive to the diagnosis of Capnocytophaga canimorsus septicaemia in a patient with no definite record of animal bites. Multiple rods were seen extracellularly and within the cytoplasm of neutrophils. The blood culture became positive after 18 h of incubation. Disseminated intravascular coagulation (DIC) was manifest and infarction of the spleen was suspected. Direct examination of peripheral blood smears could be a valuable adjunct in the diagnosis of overwhelming bacteraemia.
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Pedersen et al. (1993) studied this question.
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