Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
September 17, 2026Frontiers in AgingOpen Access

Role of essential and trace elements in chronic myeloid leukemia: associations with serum trace element profiles and hematological parameters

View Full Paper
Ask AI
Bookmark
Share

Authors

AYAjay YadavASTERUCUmesh ChoudharyBanaras Hindu UniversityAAAnupam AichUniversity of Minnesota

Discussion

Loading...

Member takes

Overview

Cross-sectional study reveals significant trace element dysregulation in chronic myeloid leukemia patients, highlighting potential roles of mineral imbalances in leukemogenesis.

Key Points

  • To assess serum concentrations of essential and toxic trace elements in patients with chronic myeloid leukemia and examine their correlations with hematological parameters.
  • Conducted a cross-sectional study in India evaluating 93 patients with chronic myeloid leukemia and 93 age- and sex-matched healthy controls.
  • Measured serum levels of chromium, copper, manganese, lead, cadmium, arsenic, iron, selenium, and zinc using atomic absorption spectroscopy alongside complete blood counts.
  • Chronic myeloid leukemia patients exhibited significantly higher serum concentrations of copper, manganese, lead, cadmium, and arsenic relative to healthy controls.
  • Healthy controls demonstrated significantly higher concentrations of chromium, iron, selenium, and zinc, with several elements showing statistically significant correlations with hematological parameters.

Cite This Study

Yadav et al. (2026) studied this question.

synapsesocial.com/papers/6aabb61e5f706d05830e49bfhttps://doi.org/10.3389/fragi.2026.1920709
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The role of redox-active iron, copper, manganese, and redox-inactive zinc in toxicity, oxidative stress, and human diseases2025 · 24 citations
  2. 2Trace elements and carcinogenicity: a subject in review2012 · 148 citations
  3. 3Diet as a Potential Moderator for Genome Stability and Immune Response in Pediatric Leukemia2021 · 7 citations
  4. 4Mechanisms of Disease Progression and Resistance to Tyrosine Kinase Inhibitor Therapy in Chronic Myeloid Leukemia: An Update2019 · 100 citations
  5. 5ASSESSMENT AND CORELATION OF OXIDATIVE STRESS BETWEEN HEALTHY ADULTS AND ADULT PATIENTS WITH CHRONIC MYELOID LEUKEMIA TREATED WITH IMATINIB2023 · 2 citations