Observational
Observational study examines HDL cholesterol efflux capacity and renal function in type 2 diabetes, highlighting links between kidney disease and impaired vascular protection.
Background: The cholesterol efflux capacity (CEC) of high-density lipoprotein (HDL) (HDL-CEC) is inversely associated with atherosclerotic cardiovascular disease. Type 2 diabetes mellitus (T2DM) is frequently complicated by chronic kidney disease (CKD), usually associated with increased homocysteine (Hcy), and these conditions are likely to be involved in HDL dysfunction. However, the relationship between HDL-CEC and CKD, as well as Hcy levels in patients with T2DM remains unclear.
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Hadano et al. (2026) conducted an observational in Type 2 Diabetes. High-Density Lipoprotein Cholesterol Efflux Capacity was evaluated on Renal function.
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