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September 17, 2026Cochrane library

Cardiorespiratory training for people with stroke

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Authors

SKSharon KramerJCJoshua CheyneSFSamantha Fawkner

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Overview

Systematic review of randomized trials finds cardiorespiratory training slightly improves fitness and mobility after stroke, suggesting modest but uncertain clinical benefits.

Key Points

  • To determine whether cardiorespiratory training after stroke reduces death and disability or improves risk factors, cardiorespiratory fitness, walking ability, and physical function compared to non-exercise controls.
  • Systematic review and random-effects meta-analysis of 53 randomized controlled trials involving 2,672 participants (mean age 61.9 years) in subacute or chronic stroke recovery phases.
  • Evaluated cardiorespiratory training interventions against non-exercise controls, usual care, attention controls, or waiting list controls using Cochrane RoB 1 and GRADE methodologies.
  • Cardiorespiratory training improved peak oxygen uptake at intervention completion (mean difference [MD] 2.37 ml/kg/min, 95% CI 1.39 to 3.36; 13 studies, 608 participants) and at follow-up (MD 2.76 ml/kg/min, 95% CI 1.36 to 4.16; 5 studies, 237 participants).
  • Training yielded a slight increase in comfortable walking speed (MD 0.08 m/s, 95% CI 0.04 to 0.12; 16 studies, 647 participants) and balance scores (Berg Balance Scale equivalent MD 2.09, 95% CI 1.10 to 3.07; 18 studies, 772 participants).
  • No measurable effects were identified for mortality or secondary vascular events at the end of training programmes or extended follow-up.

Cite This Study

Kramer et al. (2026) studied this question.

synapsesocial.com/papers/6aabb7b85f706d05830e6f30https://doi.org/10.1002/14651858.cd016000
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