Rheumatoid arthritis (RA) is a common chronic autoimmune disease characterized not only by progressive joint inflammation and structural damage but also by a wide range of systemic manifestations. Despite major therapeutic advances, RA continues to impose a substantial clinical, functional, and socioeconomic burden, contributing to disability, reduced work productivity, absenteeism, and increased healthcare utilization and costs.
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P. Santos-Moreno (2026) studied this question.
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