Campylobacter infection in adult patients with primary antibody deficiency

Genetic stability of Campylobacter coli in patients with primary antibody deficienciesThe Journal of Allergy and Clinical Immunology: In PracticeVol. 7Issue 5PreviewIn the Clinical Communication, Dion et al1 reported that in patients with severe primary antibody deficiency (PAD), Campylobacter infection is a major cause (6.5%) of chronic or recurrent diarrhea. Moreover, by a molecular study performed in a subset of 18 strains from 5 patients with recurrent infections, they demonstrated that all strains were different, even when the episodes occurred closely over time. Thus, the authors hypothesized that reinfection would be more likely than persistent colonization, although colonization with multiple strains cannot be excluded.